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Datura stramonium
My sister-in-law had this show up in her yard. We are curious what it could be.
Indeed! I read up on it and wow. She believes there were seeds in her compost. She has little ones so I think she'll be pulling it.
Solanaceae (nightshade) also known as Jimson Weed.
Powerful hallucinogen and deliriant,care must be taken with this plant.