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Passiflora lutea
Vine with curly tendrils and three-lobed leaves. Native (to the Southeastern quarter of the USA) wildflower that can become weedy and/or invasive in some areas.
Temperate forest. Rockwood Park, Virginia.
Thank you both for your suggestions. I am not sure this quite matches either ID suggestion. However, it does seem to resemble a wild cucumber of some sort. The search will continue...