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Pholiota squarrosa
Both the cap and the stem are covered in small, pointed scales that are pointed downward and backward. The crowded gills are yellowish, then later rust-brown. The mushroom has an odor that, depending on the author, has been described as resembling garlic, lemon, radish, onion, or skunk. It has a strong taste, resembling radishes. Once thought to be edible, it is now considered and known to be poisonous, especially if consumed in combination with alcohol. The mushroom contains unique chemicals thought to help it infect plants by neutralizing defensive responses employed by them
Common in North America and Europe, it is often an opportunistic parasite, and has a wide range of hosts among deciduous trees, although it can also infect conifers. It can also live as a saprobe, deriving nutrients from decomposing wood. The mushroom is typically found growing in clusters at the base of trees and stumps
The fruit bodies contain unique chemical compounds that are derived from phenylpropanoids. The compounds, named squarrosidine and pinillidine, inhibit the enzyme xanthine oxidase. Xanthine oxidase catalyzes the crystallization of uric acid in the joints, a main cause of gouty arthritis, and inhibitors of this enzyme are being used clinically to reduce this side effect. The natural function of these compounds may be to quench reactive oxygen species produced by plants as a defensive response to fungal infection
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